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Contraindicated (1)pentobarbital will lessen the extent or effect of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with robust CYP3A4 inducers just isn't advisedpentobarbital will minimize the extent or result of tipranavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warnin